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Documenting comorbidities such as cardiovascular disease, sleep apnea, type 2 diabetes risk factors, or obesity-related joint disease strengthens your case

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Animal and translational work hints at synergy between estrogen signaling and GLP-1 pathways, raising the possibility that fluctuating sex hormone states (menstrual cycle, menopause, exogenous hormones) may shape both efficacy and side-effect profiles (Vigil et al., 2022