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Impact of glp-1 receptor agonists on hospitalization for heart failure and all-cause death in patients with diabetes with and without heart failure: a real-world study | Clinical Research in Cardiology | Springer
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In the hypothalamic neurons, the IRS-PI3K signaling activates PDE3B to decrease cAMP levels and inhibit CREB activity, which suppresses the expression of NPY to induce anorexic effects of leptin [123, 124]
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