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For the treatment of non-metastatic castration-resistant and metastatic castration-sensitive prostate cancer, clinical guidelines recommend androgen receptor antagonists, such as apalutamide, in combination with androgen-deprivation therapy as the standard of care
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compared GLP-1RAs to seven non-GLP-1RA anti-diabetics, such as insulin and metformin, which are thought to affect the risk of CRC [149]
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