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In the first pathway, GLP-1RA inhibits the apoptotic mechanisms through activating phosphatidylinositol-3 kinase (PI3K), protein kinase Cฮถ (PKCฮถ), and protein kinase B (PKB), which finally leads to the inhibition of NF-ฮบB pathway and caspase activation
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Metabolic control via nutrient-sensing mechanisms: role of taste receptors and the gut-brain neuroendocrine axis
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