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Stick to the 16-week schedule and keep the weight loss to around 0.5 to 1.0 kg a week
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In skeletal muscle, high-fructose feeding normally blunts Akt and GLUT4 translocation, yet eight weeks of oral BBR reversed these defects while raising the AMP/ATP ratio and activating AMPK—again without relying on canonical PI3K-Akt insulin signaling [77]
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