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Phase 2 Trial of Retatrutide for Obesity | New England Journal of Medicine

Evidence Rating Level: 1 (Excellent) Study Rundown: Patients who have heart failure with preserved ejection fraction often have multiple comorbidities such as obesity and hypertension, which leads to severely impaired quality of life and adverse hemodynamic and clinical features

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Patients should also seek medical advice if headaches are associated with persistent vomiting, as this combination can lead to dehydration and electrolyte disturbances